Skincare backed with research
ISB-HE02
Patent Registration 10-2023-169400
The Future of Skin Science
We derive our skincare technology from Allogeneic Myocardium-Derived Adult Stem Cell Extracellular Vesicles. The technology of allogenic myocardium-derived stem cells was originally targeted to use as a treatment for patients with rheumatoid arthritis, Duchenne muscular dystrophy, autoimmune and neurodegenerative diseases. When applied to skincare, the extracellular vesicles (EVs) from myocardium-derived adult stem cells have potential to innovate skincare paradigm. We aim to resolve dermatological problems not just on a surface level, but by targeting molecular mechanisms of the skin and resolving the core issue.
The Technology Behind Our Skincare
High-Purity
Advanced Isolation Technology
High-purity, high-efficiency biopharmaceutical production. 3D, homeostasis-mimicking culture.
3-Year Stability
Ready-to-Inject Freezing Formula
A stable, long-shelf-life formula for consistent efficacy.
The science behind our skincare
Multimodal mechanism of action of MyoCSC
Anti-inflammation and Immune Modulation
Effects
- Calming effect on the skin & inhibits melanin production
- Fine-tones the skin
Mechanisms
- Anti-inflammation: IL-6 and miR-146a for inducing M1-M2 polarization
- Immune modulation: IDO, PGE2 and miR-146a to suppress Th1/Th17 response, induce Th2 response
Extracellular Matrix Remodeling
Effects
- Anti-aging effect, collagen synthesis, strengthens skin barrier
Mechanisms
- Indirect angiogenesis: Ang-1, HGF, SDF-1, VEGF
Angiogenesis & Wound Healing
Effects
- Stimulates fibroblast growth and collagen synthesis
- Skin regeneration & anti-aging effect
Mechanisms
- Anti-apoptosis/wound healing: SDF-1, IL-6, HGF for recruiting endogenous stem cells
Proven Efficacy
1.Angiogenesis
Quantity and Time-dependent growth
2.Induction of dermal fibroblast growth
3.Regeneration of muscle fiber & Anti-inflammation
Decreased activity of caspase regulates apoptosis and inflammation.
